The number of containers transshipped at deep-sea ports, such as the port of Rotterdam, is increasing yearly. Therefore, transporting containers from the deep-sea port to the hinterland is also becoming more and more complex. In this dissertation, two types of operational problems concerned with inland transportation are studied. First, what is the most cost-efficient and reliable way to transport containers to an inland terminal using barges and trucks? Second, what is the best way for a crane driver on a terminal to reposition containers if he or she has some idle time? These problems originate from a close collaboration with an inland terminal in the port of Amsterdam and are modeled as mathematical optimization problems and solved using Operations Research techniques, such as Integer Linear Programming, Stochastic Programming, and Local Search heuristics.